The fifth edition of the Textbook of Biochemistry incorporates significant revisions that emphasize the clinical orientation and integration aspects of the CBME syllabus. It thus includes a larger number of case studies throughout the text for providing students with early clinical exposure, as well as vertical and horizontal integration boxes that show the relationship between biochemistry and other medical subjects. The revisions also ensure that the CBME syllabus is complied with in all respects and the book continues to provide undergraduate medical students with an easy-to-understand overview of biochemistry concepts. The book will also be a valuable study resource for students of allied health fields and those preparing for competitive examinations.
Special features of this edition
Rafi MD is the Dean and Medical Director of Surabhi Institute of Medical Sciences, Siddipet, Telangana.
A Mapping of the Contents to Competency-Based Undergraduate Curriculum (CBME) Preface to the Fifth Edition Preface to the First Edition How to Use This Book
I Prelude — Molecular and Functional Organisation of Life 1. Learning Biochemistry 2. The Cell and Biological Membranes: Structure and Function
II Molecules of Life 3. Carbohydrates 4. Lipids 5. Amino Acids and Proteins 6. Nucleotides and Nucleic Acids 7. Enzymes 8. Clinical Enzymology 9. Fat-Soluble Vitamins 10. Water-Soluble Vitamins
III Physiological Biochemistry 11. Biochemistry of Blood 12. Hemoglobin and the Chemistry of Respiration 13. Heme Synthesis and Degradation 14. Digestion and Absorption
IV Metabolism 15. A Journey into Metabolism 16. Central Metabolism: Biological Oxidation 17. Metabolism of Carbohydrates 18. Blood Glucose Homeostasis—Hormones of the Pancreas and Diabetes Mellitus 19. Metabolism of Lipids 20. Metabolism of Cholesterol, Lipoproteins and the Diseases Associated with Lipid Metabolism 21. Metabolism of Amino Acids – General Aspects 22. Metabolism of Individual Amino Acids and Diseases Associated with Them 23. Metabolism of Nucleotides 24. Integration of Metabolism 25. Metabolism of Xenobiotics: Detoxification
V Nutrition 26. Minerals 27. Principles of Nutrition
VI Clinical Biochemistry 28. Water and Electrolytes 29. Acid–Base Balance 30. Organ Function Tests 31. Biochemistry of Cancer
VII Molecular Biology 32. DNA Metabolism 33. RNA Metabolism 34. Protein Biosynthesis 35. Regulation of Gene Expression
VIII Biotechnology and Immunology 36. Recombinant DNA Technology 37. Molecular Diagnostics 38. Biochemical Techniques 39. Immunochemistry
IX Biochemical Perspective of Endocrinology 40. Hormone Action 41. Hypothalamic and Pituitary Hormones 42. Thyroid Hormones 43. Hormones of the Adrenal Gland 44. Hormones of the Gonads
X Contemporary Topics 45. Extracellular Matrix 46. Reactive Oxygen Species and Antioxidants 47. Biochemical Genetics 48. Environmental Pollutants, Toxins and Biomedical Waste Management 49. Human Genome Project and Bioinformatics 50. Gene Therapy
Appendixes A1 Attitude, Ethics and Communication (AETCOM) A2 Reference Values and Interpretation of Biochemical Parameters: A Ready Clinical Reference Index
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